Synthesis icon
Synthesis
Tel: (866) 995-5100
e-mail: Use our inquiries form
back to Synthesis home page

Resource Library

   

Introduction Application Notes Literature Web Links

Review Articles

request reprint Boufatah, Narimène; Gellis, Armand; Maldonado, José; Vanelle, Patrice.
"Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity"
Tetrahedron, 2004, 60, 41, 9131–9137.
Article demonstrates: higher yield, shorter reaction time, easier purification, specific non-thermal microwave effect. Features START system.

request reprint Biswas, Atanu; Sessa, David J.; Lawton, John W.; Gordon, Sherald H.; Willett, J.L.
"Microwave-Assisted Rapid Modification of Zein by Octenyl Succinic Anhydride"
American Association of Cereal Chemists, Inc., Vol. 82, No. 1, 2005.

request reprint Strohmeier, Gernot; Kappe, C. Oliver.
"Rapid Generation of Polymer-Bound Enones by Microwave-Assisted Solid-Phase Synthesis"
6th Annual High-Throughput Organic Synthesis, Feb. 2001, San Diego, CA.

request reprint Wiesbrock, Frank; Hoogenboom, Richard; Schubert, Ulrich.
"Microwave-Assisted Polymer Synthesis: State-of-the-Art and Future Perspectives"
Macromol. Rapid Commun., 2004, 25, 1739–1764.

request reprint Nücher, M.; Ondruschka, B.; Tied, A.; Lautenschläger, W.; Borowski, K.
"Using a Microwave Labstation for Parallel Synthesis and Combinatorial Chemistry"
American Genomic/Proteomic Technology, Sep/Oct 2001, 34-39

read online Horeis, G.; Pichler, S.; Stadler, A.; Gössler, W; and Kappe, C.
"Microwave-Assisted Organic Synthesis - Back to the Roots"
Fifth International Electronic Conference on Synthetic Organic Chemistry (ECSOC-5), 30 August (2001)

request reprint Varma, R. S.
"Solvent-Free Organic Synthesis Using Supported Reagents and Microwave Irradiation"
Green Chem. 43-55 (1999)

request reprint Varma, R. S.
"Solvent-Free Synthesis of Heterocyclic Compounds Using Microwaves"
J. Heterocycl. Chem. 36 , 1565-1571 (1999)

request reprint Strauss, C. R.
"A Combinatorial Approach to the Development of Environmentally Benign Organic Chemical Transformations"
Aust. J. Chem. 52, 83-96 (1999)

read online Gabriel, C.; Gabriel, S.; Grant, E. H.; Halstead, B. S. J.; Mingos, D. M. P.
"Dielectric Parameters Relevant to Microwave Dielectric Heating"
Chem. Soc. Rev. 27, 213-223 (1998)

request reprint Gedye, R.N.; Wei, J.B.
"Rate Enhancement of Organic Reactions by Microwaves at Atmospheric Pressure"
Can. J. Chem. 76, 525-532 (1998)

request reprint Bose, A. K.; Banik, B. K.; Lavlinskaia, N.; Jayaraman, M.; Manhas, M. S.
"More Chemistry in a Microwave"
Chemtech 27, 18-24 (1997)

request reprint Caddick, S.
"Microwave Assisted Organic Reactions"
Tetrahedron 51, 10403-10432 (1995)

request reprint Strauss, C. R.; Trainor, R. W.
"Developments in Microwave-Assisted Organic Chemistry"
Aust. J. Chem. 48, 1665-1692 (1995)

request reprint Westaway, K. C.; Gedye, R.
"The Question of Specific Activation of Organic Reactions by Microwaves"
J. Microwave Power Electromagn. Energy 30, 219-230 (1995)

request reprint Baghurst, D. R.; Mingos, D. M. P.
"Application of Microwave Dielectric Heating Effects to Synthetic Problems in Chemistry"
Chem. Soc. Rev. 20, 1-47 (1991)


Articles

Read Online Leadbeater, Nicholas.
Making Microwaves: Microwave technology in organic synthesis
Chemistry World, January 2004.

request reprint Corsaro, Antonio; Chiacchio, Ugo; Pistara, Venerando; Romeo, Giovanni.
Microwave Assisted Chemistry of Carbohydrates
Current Organic Chemistry, 2004, 8, 511–538

request reprint Shieh, Wen-Chung; Dell, Steven; Repic, Oljan
"1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and Microwave-Accelerated Green Chemistry in Methylation of Phenols, Indoles, and Benzimidazoles with Dimethyl Carbonate"
Organic Letters, ASAP Article 10.1021/o1016949n S1523-7060(01) 06949-8, Web Release Date: November 22 (2001)

request reprint Kappe, C. O.
"Speeding Up Solid-Phase Chemistry by Microwave Irradiation. A Tool for High-Throughput Synthesis"
Am. Lab. 33, (10) 13-19 (2001)

request reprint Varma, R. S.
"Solvent-Free Accelerated Organic Syntheses Using Microwaves"
Pure Appl. Chem. 73, 193-198 (2001)

request reprint Deshayes, S.; Liagre, M.; Loupy, A.; Luche, J.-L.; Petit, A.
"Microwave-Activation in Phase Transfer Catalysis"
Tetrahedron 55, 10851-10870 (1999)

request reprint Varma, R. S.; Naicker, K. P.; Kumar, D.; Dahiya, R.; Liesen, P. J.
"Solvent-Free Organic Transformations Using Supported Reagents and Microwave Irradiation"
J. Microwave Power Electromagn. Energy 34, 113-123 (1999)

request reprint Varma, R. S.
"Solvent-Free Organic Synthesis on Mineral Suports Using Microwave Irradiation"
Clean Products and Processes 1, 132-147 (1999)

request reprint Fini, A.; Breccia, A.
"Chemistry by Microwaves"
Pure Appl. Chem. 71, 573-579 (1999)

request reprint Varma, R. S.
"Microwave-Assisted Reactions Under Solvent-Free 'Dry' Conditions"
in Microwaves: Theory and Application in Material Processing IV, Clark, D.; Sutton, W.; Lewis, D. (Eds.), American Ceramic Society, Ceramic Transactions 80, 357 (1997)

request reprint Majetich, G.; Hicks, R.
"The Use of Microwave Heating to Promote Organic Reactions" J. Microwave Power Electromagn. Energy 30, 27 (1995)

request reprint Gedye, R. N.; Smith, F. E.; Westaway, K. C.
"Microwaves in organic and organometallic synthesis"
J. Microwave Power Electromagn. Energy 26, 3-17 (1991)

read online Cumming, S.
"Award for Microwave chemistry"
Green Chem.1, G94-G96. (1999)

request reprintKappe, C. Oliver.
Microwave-enhanced Chemistry — Enabling Technology Revolutionising Organic Synthesis and Drug Discovery
Business Briefing: Future Drug Discovery (2003)


Feature Articles

request reprint Dr. Richard Wagner
Microwave-assisted synthesis in the pharmaceutical industry: a current perspective and future prospects
Drug Discovery World, Summer 2006, pp. 59–66.

request reprint Calum Macleod, Blanca Martinez-Teipel, Roland E. Dolle
Solid/solution phase annulation (SPAnTM) technology: Single-step derivatization of primary amines to piperazines on solid-phase
Poster Presentation, ACS Show 2004

read online Schoenfeld, C.; Favretto, L.; Loechner, M.
"Microwave Synthesis Comes to the Academic Laboratory"
American Laboratory, November 2003.

request reprint Richter, R. C.; Link, D.; Kingston, H. M.
"Microwave-Enhanced Chemistry"
Anal. Chem. 31A-37A (2001)

read online Whittaker, G.
"Fast and furious"
New Scientist, p. 34. February 28, 1998

request reprint Dagani, R.
"Molecular Magic With Microwaves"
Chem. Eng. News p. 26-33, February 10, 1997.


Books & Monographs

Buy Book Microwave-Enhanced Chemistry. Fundamentals, Sample Preparation, and Applications, Kingston, H. M. and Haswell, S. J. (Eds), American Chemical Society, 1997.

Buy book Microwaves in Organic Synthesis, Loupy, A. (Ed), Wiley-VCH.


Offline Articles

Santagada, V.; Perissutti, E.; Caliendo, G.
"The Application of Microwave Irradiation as New Convenient Synthetic Procedure in Drug Discovery"
Current Medicinal Chemistry, 2002, 9, 1251-1283

Larhed, M.; Hallberg, A.
"Microwave-Assisted High-Speed Chemistry: A New Technique in Drug Discovery"
Drug Discovery Today, 6, 406-416 (2001)

Elander, N.; Jones, J. R.; Lu, S.-Y.; Stone-Elander, S.
"Microwave-Enhanced Radiochemistry"
Chem. Soc. Rev. 239-250 (2000)

Loupy, A.; Petit, A.; Hamelin, J.; Texier-Boullet, F.; Jacquault, P.; MathŽ, D.
"New Solvent-Free Organic Synthesis Using Focused Microwaves"
Synthesis, 1213 (1998)

Langa, F.; de la Cruz, P.; de la Hoz, A.; D’az-Ortiz, A.; D’ez-Barra, E.
"Microwave Irradiation: More Than Just a Method for Accelerating Reactions"
Contemp. Org. Synth. 4, 373-386 (1997)

Abramovitch, R. A.
"Application of Microwave Energy in Organic Chemistry - A Review"
Org. Prep. Proced. Int. 23, 685-711 (1991)

Rabinovich, Alex, Senior Scientist, Combinatorial Chemistry Technologies, Pfizer Inc.
"The Scale-up of Microwave-Assisted Organic Reactions"

Sha, Y.W.; Wang, Y.; Ge, J.; Wang, X.
"Application of Microwave Irradiation in the Synthesis of Heterocyclic Compounds"
Chin. J. Org. Chem. 21, 102-115 (2001) (in chinese).

Kidawi, M.
"Dry Media Reactions"
Pure Appl. Chem. 73, 147-151 (2001)

<Loupy, A.; Perreux, L.; Liagre, M.; Burle, K.; Moneuse M.
"Reactivity and Selectivity Under Microwaves in Organic Chemistry. Relation With Medium effects and Reaction Mechanisms"
Pure Appl. Chem. 73, 161-166 (2001)

Yadav, J. S.; Meshram, H.M.
"Green Twist to an Old Theme. An Eco-Friendly Approach"
Pure Appl. Chem. 73, 199-203 (2001)

Romanova, N. N.; Kudan, P. V.; Gravis, A. G.; Bundel', Y. G.
"Application of Microwave Activation in the Chemistry of Heterocyclic Compounds"
Khim. Geterotsikl. Soediin. 1308-1320 (2000)

de la Hoz, A.; Langa, F.
"Microwave Irradiation in Solvent-Free Conditions: An Eco-Friendly Methodology to Prepare Indazoles, Pyrazolopyridines and Bipyrazoles by Cycloaddition Reactions"
Green. Chem. 2, 165-172 (2000)

Krstenansky, J. L.; Cotterill, I.
"Recent Advances in Microwave-Assisted Organic Synthesis"
Curr. Opin. Drug Discovery Dev. 4, 454-461 (2000)

D. Bogdal
"Microwaves - Application to Organic Synthesis"
Wiad. Chem. 53, 66-93 (1999) (in polish).

Rao, K. J.; Vaidhyanathan, B.; Ganguli, M.; Ramakrishnan, P. A.
"Synthesis of Inorganic Solids Using Microwaves"
Chem. Mater. 11, 882-895 (1999)

Loupy, A
"Solvent-free reactions"
Topics Curr. Chem. 206, 153-207 (1999)

Combs, A.; Saubern, S.; Rafalski, M.; Lam, P.
"Solid Supported Aryl/heteroaryl C-N Cross Coupling Reactions"
Tetrahedron Letters, 40, 1623-1626 (1999)

Almena, I.; Carrillo, J. R.; de la Cruz, P.; Diaz-Ortiz, A.; Gomez-Escalonilla, M. J.; de la Hoz, A.; Langa, F.; Prieto, P.; Sanchez-Migallon, A.
"Application of Microwave Irradiation to Heterocyclic Chemistry"
Targets in Heterocyclic Chemistry 2,, 281-308 (1998)

Sridar, V.
"Microwave-Radiation as a Catalyst for Chemical Reactions"
Current Science 74, 446-450 (1998)

Mingos, D. M. P.; Whittaker, A. G.
"Microwave dielectric heating effects in chemical synthesis"
in Chemistry under Extreme or Non-Classical Conditions, von Eldik, R.; Hubbard, C. D. (Eds), Wiley: New York,, 479-514 (1997)

Galema, S. A.
"Microwave chemistry"
Chem. Soc. Rev. 26, 233-238 (1997)

Chen, S.-T.; Tseng, P.-H.; Yu, H.-M.; Wu, C.-Y.; Hsiao, K.-F.; Wu, S.-H.; Wang, K.-T.
"The Studies of Microwave Effects on the Chemical Reactions"
J. Chin. Chem. Soc. 44, 169-182 (1997)

Majetich, G.; Hicks, R.
"Applications of Microwave-Accelerated Organic Synthesis"
Rad. Phys. Chem. 45, 567-579 (1995)

Berlan, J.
"Microwaves in Chemistry: Another Way of Heating Reaction Mixtures"
Rad. Phys. Chem. 45, 581-589 (1995)

Jacob, J.; Chia, L. H. L.; Boey, F. Y. C.
"Thermal and nonthermal interaction of microwave-radiation with materials"
J. Mater. Sci. 30, 5321-5327 (1995)

Majetich, G.; Hicks, R.
"Applications of Microwave-Accelerated Organic Chemistry"
Res. Chem. Intermed. 20, 61 (1994)

Mingos, D. M. P.
"The Application of Microwaves in Chemistry"
Res. Chem. Intermed. 20, 85-91 (1994)

Loupy, A.; Bram, G.; Sansoulet, J.
"Anion Activation in Solvent-Free Heterogeneous Solution - Use of Microwave-Ovens"
New J. Chem. 16, 233-242 (1992)

Bram, G.; Loupy, A.; Villemin, D.
"Microwave Activation of Organic Reactions"
in Solid Supports and Catalysts in Organic Synthesis, Smith, K. (Ed), Ellis Harwood:London (1992)

Bradley, D.
"The Nuke's the Thing for Synthesis"
Modern Drug Discovery 4, 32-36 (2001)

Cresswell, S. L.; Haswell, S. J.
"Microwave Ovens - Out of the Kitchen"
J. Chem. Educ.78, 900-904 (2001)

Brain, C. T.
"Are Microwave Instruments Just Expensive Hot-Plate Stirrers?"
Drug Discovery Today 6, 663 (2001)

Edwards, P.
"More Microwave Reactors Required"
Drug Discovery Today 6, 614 (2001)

Cresswell, S. L.; Haswell, S. J.
"Cooking up a Storm"
Chem. Ind. 621-624 (1999)

Stinson, S.
"Use of Microwave Heating to Speed Organic Reactions Continues to Grow"
Chem. Eng. News p. 45-46, May 20, 1996

Mingos, D. M. P.
"Microwaves In Chemical Synthesis"
Chem. Ind. 596-599 (1994)

Continue to web links —>



Synthesis: See overview, or continue to fundamentals, technical details, or accessories.
General: Go to the Milestone front page, or send us an inquiry.