Reaction optimization or parallel format scale-up?
The Milestone MicroSYNTH offers unique tools to work with the entire range of volumes in the synthetic process, from low volume optimization to parallel format scale-up.
The MicroSYNTH system and its accessories are developed to carry out every kind of reaction under classical heating.
Reaction optimization SV and BSV setup
This package includes a 45 mL quartz vessel which allows to perform reactions at temperature up to 250°C and pressure up to 40 bar. The vessel is hosted in a safety shield which features a built-in pressure control through a preloaded spring with vent-and-reseal mechanism.
A special PTFE cover is equipped with ports for direct temperature and pressure control. An optional cover permits to flush the reactor with inert gas, or to pre-load a gaseous reactant for gas-liquid reactions. Rapid cooling is ensured by a stream of compressed air.
The SV package also includes a PTFE reaction vessel with a PEEK shield, suitable for all the applications where improved chemical resistance is required, or higher pressures (up to 100 bar) are expected.
Large batch reactions NP setup
In this way, any chemical reaction currently performed with a hot plate, heating mantle, or oil bath can be immediately transferred to the microwave.
This will permit the chemist to investigate the effects of microwaves on reaction rates and mechanism.
Parallel format scale-up QK and SK setup
A fully automated capping system is also available from Milestone to enhance the automation of the synthetic process.
When scaling up a reaction under conditions of extremely high temperature and pressure, there is no better choice than the HPR rotor; this rotor accommodates up to 10 SK-10 reactors, each of which can be individually inserted in the MicroSYNTH microwave cavity.